AGING & LONGEVITY

LIFESTYLES

EXERCISE

NUTRITION

NUTRITIONAL SUPPLEMENTATION

HORMONAL BALANCE

BIOMARKERS

Scientific articles

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Ageing and Longevity

The population of centenarians represents the maximum exponent of longevity. hese people are characterised by the late emergence (more than ninety years) of age-related diseases in their lives, its associated disability and its irreversible process towards death. The study of the biomarkers which characterise this population is of high scientific value. The exceptional phenotype of centenarians is determined both by environmental factors and genetic ones. In this study, 62 genetic variants related to cardio-metabolic diseases, cancer and longevity have been compared in a group of Spanish people older than 100 and the healthy controls of the same ethnic origin. The Genetic Score (GC) of the people over 100 showed a lower predisposition to hypertension, ‘overall cancer risk and to ‘other types of cancer’, but did not show differences in the rest of the genetic variants among which were related to cardiovascular disease, thrombotic stroke, dyslipidemia, lung cancer, breast cancer or extreme longevity. In conclusion, environmental factors (nutrition, stress, exercise, control of biomarkers, etc.) powerfully determine longevity. The main objective of Neolife’s age management programmes is not to increase life expectancy but to prolong a good quality of life and delay the emergence of age-related diseases through the intervention of environmental factors. However, this intervention is precisely what characterises the population of people over 100.